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Pharma: Most Popular Articles

These articles are the most popular over the last month.
Patent Cliff
Numerous popular drugs began losing market protect in 2011. The trend will continue through 2016.
Prescription Medication Trends
Records were broken in the number of prescriptions filled in the United States in 2010. The majority of prescriptions were for generics rather than brand-name drugs.
FDA Approves Viibryd
Viibryd, marketed by Clinical Data, is the first new type of antidepressant to be approved in a decade.
Drug Master File
A drug master file is a document submitted by an Active Pharmaceutical Ingredient manufacturer to the FDA.
Direct Marketing to Physicians
Amid an evolving health care landscape, marketing pharmaceuticals to physicians has grown more complicated.
API
API (Active Pharmaceutical Ingredient) definition and example
OTC Drug Industry
The global market for over-the-counter drugs is predicted to reach $70 billion by 2015. While sales of OTC drugs are declining in some countries, sales are growing in the United States and Western Europe. Cough and cold medicines and painkillers lead the list of top-selling OTC medications.
MS Drugs
Top selling multiple sclerosis (MS) drugs
Pharma News Sites
Online sources for keeping up-to-date on pharmaceutical industry news and trends.
Pharmaceutical Research Funding
Private industry is the largest source of pharmaceutical research funding in the United States, followed by government, foundations, charities and individual donors. What's behind the changes in funding for research and development?
Top Generic Drug Companies
Generic drugs may soon eclipse branded medicines in sales as well as volume, even in the world's largest markets.
Best Biotechs and Pharmas to Work for
An annual survey of pharmaceutical and biotech employees reveals that some companies are still investing in their workforce, despite massive lay-offs in the industry over the past 10 yearrs.
Bioavailability
Bioavailabilty is a term used in pharmacology.
Antidepressant Market
Prescriptions for antidepressants are at a record high but generic competition means this class of drugs are no longer blockbusters for their sponsoring companies.
CGMP
The FDA develops minimum standards for the design, monitoring and control of pharmaceutical manufacturing processes and facilities.
Biologic License Application (BLA)
Definition of the term Biologic License Application.
diabetes drug pipeline
Several new classes of anti-diabetes drugs in the pipeline have the potential to better control blood glucose levels than existing drugs.
PDUFA
PDUFA V, the latest iteration of the Prescription Drug User Fee Act includes new provisions for generic and biosimilar user fees.
IP Laws and Pharma
International property (IP) laws are both legal and business assets for pharmaceutical manufacturers.
Branded Drug Sales for 2011
Sales of top selling branded drugs in 2011.
HIV Drugs
Market leaders in HIV treatments are being pressured to lower costs to make their drugs accessible in countries that have the highest incidence of infection even as they face growing generic competition.
Emerging Markets
India is already a world leader in the generic drug market with 3,500 pharmaceutical manufacturers exporting about $10 billion annually to more than 100 countries. With many more brand name drugs going off patent in 2012, India plans to expand its role as key supplier to the largest drug markets in the United States and Europe, as well as emerging markets. India is also looking at future growth as a leader in contract manufacturing of brand-name prescription drugs and host for clinical trials which cost about one-tenth of a clinical trial conducted in the United Sates, according to a Ministry of Commerce and Industry strategy report.
Drug Classifications
How are drugs classified? What are the different types of drug classes? How many types of drugs are there? Classifications of pharmaceutical drugs
Pharmas Test Russia Opps
It's a relatively small pharmaceutical market in the global scheme of things, but Russia is attracting
Definition
: Biosimilar s, sometimes referred to as biogenerics, are highly similar versions of biologics , those
Pharma Apps
Pharmaceutical companies are developing useful -- not just promotional -- apps for physicians.
research articles
Each journal has its own requirements for how a research manuscript should be organized but they all require the basic elements.
Pharmas in Brazil
Brazil's stable economy makes it attractive to pharmaceutical investors.
R&D Spending
The pharmaceutical industry has invested more than $1 trillion on research and development (R&D) over the last decade. Industry analysts predict there's much more to come.
Biobetter
A biobetter is a recombinant protein drug in the same class as an existing biopharmaceutical but is an improved over the original drug.
ANDA
An Abbreviated New Drug Application, ANDA, is submitted to the FDA when seeking approval of a generic drug product.
New Drug Application (NDA)
Definition of New Drug Application
Training in Clinical Trials
Principal investigators seeking a federal grant to conduct clinical research and FDA approval for a pharmaceutical product must demonstrate their knowledge in conducting clinical trials.
Vintage Medicine Ads
Mrs. Winslow's Soothing Syrup was marketed for teething babies.
Gardsail
Since Gardasil went on the market in 2006, more than 20,000 adverse events have been reported but the CDC says no serious complications have been proven to have been caused by the disease.
Prescription Drug Fee
Calculating the Branded Prescription Drug Fee is a complex process that requires several government health programs to report sales data to the IRS annually.
Specialty Pharmacy
The growth of specialty pharmacy services. What is a specialty pharmacy? What services to specialty pharmacies provide?
All About Viibryd
Background information on Forest Laboratories' Viibryd.
Diabetes drugs
Companies wishing to introduce a new drug therapy into the U.S. market must obtain Food and Drug Administration (FDA) approval. It’s the company’s responsibility to test the drug and provide evidence that it’s safe and effective. The FDA does not test drugs. The agency’s Office of Testing and Research conducts limited research in the areas of safety, quality and effectiveness.
Anti-Obesity Drug Trends
The outlook for the anti-obesity drug market is tepid despite global obesity epidemic.
Generic drug launches
Common pitfalls of generic drug launches.
Double-Blind Trial
Definition of double-blind trials
National Drug Code
Description of the National Drug Code (NDC), how the codes are applied and how the data is collected for the electronic NDC directory.
Generic pipeline
As big name legacy drugs continue to go off patent, numerous new generic drugs are scheduled to enter the marketplace.
Authorized Generic
What authorized generics are and why they are controversial.
GlaxoSmithKline (GSK)
UK-based GlaxoSmithKline was the third largest pharmaceutical company in the world, behind Johnson & Johnson and Pfizer, according to Fortune’s annual rankings.
Black box warning
It is the most serious medication warning required by FDA.
2012 drugs
The U.S. Food and Drug Administration approved 35 new drugs in fiscal year 2012, the same as in 2011.
OTC Drugs
About six-in-10 medications now sold in the United States are non-prescription drugs.
Pharmas and Reform
The pharmaceutical industry is responding to changes brought about by the Affordable Care Act with workforce restructuring, investment in new markets, more mergers and acquisitions and new marketing initiatives.
Physician Attitudes
Do physicians want to hear from industry representatives? In general, they do, although with restrictions that protect their professional integrity.
International Ads
Some of these ads make me facepalm. Some make me scratch my head. Others make me laugh. One thing they have in common is that you're not likely to see them if you're an American consumer. For one thing, these are all international ads. Some ideas and images just don't translate well.
Alternatives to Warfarin for Stroke Prevention
New drugs designed to compete with warfarin, the once standard treatment for irregular heartbeat, are entering the market. Some may not be any safer than warfarin.
Emerging Market Spending
If the current trend continues, drug spending in emerging markets could match that of the United States in a few years.
China Market
An overview of the challenges and opportunities in the China pharmarmaceutical market.
Pfizer
Pfizer is the world's largest biopharmaceutical company in terms of revenue.
Drug Shortages
The number of new drug shortages has been steadily rising each year. What are the causes? What steps are being taken to reduce drug shortages?
Top U.S. Pharmas
Which companies lead the U.S. pharmaceutical industry?
Johnson & Johnson (J&J)
U.S.-based Johnson & Johnson is the largest health care product company in the world. It has been headquartered in New Brunswick, New Jersey since its founding.
Branded Drug Sales in 2010
The global pharmaceutical and market grew to $850 billion in sales in 2010.
Drugs Approved in 2011
The FDA approved 35 new drugs in 2011, including novel drugs for late-stage lung cancer, metastatic breast cancer and hepatitis C.
Drug Importation
Opponents of liberalizing drug importation continue to convince a majority in Congress to vote against it but proponents have vowed to change the policy.
Clinical Trials Phases
The four main phases of clinical trials are separate stages in the drug approval process.
Wikileaks Cables and Pharmas
Wikileaks cables provide insight into the pharmaceutical industry's negotiations with foreign governments.
Stopping The Counterfeit Drug Trade
The counterfeit drug trade has increased sharply in recent years. Counterfeit medicines are a public health threat and cost the pharmaceutical industry sector $75 billion, according to World Health Organization (WHO) estimates.
Data Mining
The use of physicians’ prescribing data for pharmaceutical marketing is a contentious issue that pits medical record privacy against corporate ‘free speech.’
Meth Addition Drug
Ibudilast, a drug compound developed by a pharmaceutical company in Japan and licensed to San Diego,
Bioinformatics
Bioinformatics combines molecular biology with computer science and information technology.
AdverseEvents Inc.
Adverse Events Inc is one of a small group of companies that have begun to commercialize the FDA Adverse Events Reports database to make it more user-friendly for consumers and businesses.
DTC
Direct advertising to consumers has been an effective marketing strategy for pharmaceutical companies but the practice continues to be heavily criticized.
Orphan Drugs
Description of orphan drugs along with examples
Adverse Event Reporting
Some US firms are aggregating and reformatting the FDA's drug side effects data to make it more useful for individuals, researchers and companies.
Biosafety Levels
Biosafety Levels
Repurpose Drugs for MS
Two research groups in Europe are exploring re-purposed drugs for multiple sclerosis.
New Tracer for AD Diagnosis
The race to develop tools for diagnosing Alzheimer's disease in vivo has yielded five promising techniques –- one of which recently received FDA approval. Ironically, the tests have arrived in advance of therapies to cure or radically change the course of Alzheimer's.
ARMs
Antibody-recruiting molecules (ARMs)are a new class of molecules under development that could lead to new ways to treat cancer and autoimmune diseases according to researchers.
Rare Diseases Products
FDA incentive programs for orphan drug development for rare diseases.
Patent Reform Act
The Leahy-Smith America Invents Act makes major changes to U.S. patent law. Pharmaceutical industry trade groups like PhRMA and BIO endorse it; GPhA has reservations.
Drug Discoveries
Medical advancements over the last 100 years have nearly doubled life expectancy
Gene Patents
The controversy over the patenting of human genes has landed in federal courts but the fight is far from over.
War on AIDS
UNAIDS says the global incidence of new HIV infections is in decline due to new preventative drugs. The joint collaboration of global health agencies says it's now feasible to expect an end to the HIV/AIDS epidemic in the foreseeable future.
Adiiction Medications
A summary of the drugs that have been developed to help people manage withdrawal and abstinence and a peek at anti-addiction drugs now under development.
Pharmas and FDA Inspections
As of 2010, the Food and Drug Administration (FDA) inspected almost all U.S. based pharmaceutical plants annually.
CER
The federal government allocated $1.1 billion for comparative effectiveness research in 2009.
pharma philanthropy
Philanthropy in the pharmaceutical industry is not just doing the right thing, it's also a key business development strategy.
Adverse Event Reporting (AER)
Definition of Adverse Event Reporting
Pediatric Drug Trials
Although children are more likely than adults to suffer from diseases, there's a dirth of clinical trials devoted to pediatric patients, partly due to a lack of protocols and partly due to a lack of financing.
Pay For Delay Agreements
Those that want the process stopped say the pay-for-delay agreements violate federal antitrust laws.
Lifestyle Drugs
Although not medically necessary, lifestyle and cosmetic drugs have carved out a piece of the global pharmaceutical market.
More Uses for Botox
Physicians in many specialties use botulinum toxin to treat everything from facial wrinkles to cervical dystonia. More applications are on the way.
Merger Mania
With fewer new drugs coming to market and brand name drugs losing their market protection from generics, big companies turned to cross-border mergers and acquisitions for continued growth.
Behind The Counter Drugs
Like over-the-counter drugs, a behind-the-counter category of drugs would be available without a doctor’s prescription, but consumers would be required to consult with a pharmacist in order to purchase the medications.
What is A Drug
Modern drugs evolved from plants but most drugs today are synthetic and are developed using advanced technology and processes.
Vaccine Development
From pre-clinical research to FDA review, the vaccine development process can take a dozen years to see a successful drug candidate to completion.
Baxter International Inc.
Baxter International, a Fortune 500 company, makes both prescription drugs and medical devices.
protein misfolding
Misfolded proteins can cause neurogenerative diseases due to molecular stress and interference with the cell function.
Pharmas and the Stop Internet Piracy Act
Is the Stop Internet Piracy Act (SOPA) a solution to online copyright infringement or a tool for managing competition and freedom if speech on the web?
Teva Pharmaceutical Industries
Teva develops, manufactures and markets generic and branded pharmaceutical drugs and active pharmaceutical ingredients.
A Decade of Changes In Store For Pharmas
The 2010 health care reform law will have direct and indirect implications for the pharmaceutical industry over the next decade.
Smoking Cessation Drugs
Analysts predict the world market for smoking cessation will grow through 2022.
TB Drug Pipeline
After several decades without any new tuberculosis treatments, global collaborations of pharmaceutical companies, governments and philanthropists promise new drugs will be arriving soon.
SCOTUS Rules on Health Reform
Reactions to the SCOTUS decision
Male Contraceptives
Researchers around the globe doggedly continue their research into viable and reversible forms of male contraception.
Negotiating Part D
Policy-makers are divided on whether the government should have authority to negotiate bulk drug prices on behalf of seniors enrolled in the Medicare program.
Physicians and Non-Compliant Patients
A survey of American Academy of Pediatrics members found that, on average, 21 percent of Midwestern practitioners discharged families from their practice for continued refusal of vaccines.
Pharmas Tackle Tropical Diseases
A dozen pharmaceutical companies, several governments and global agencies and the Bill & Melinda Gates Foundation announce a joint effort to eliminate or control neglected tropical diseases by 2020.
Thimerosal in Vaccines
A UN environmental health council reviews a draft treaty that bans global use of thimerosal in vaccines on January 13, 2012.
Younger Physicians and Vaccines
As familiarity with disease outbreaks has faded, physicians as well as parents are taking a more complacent view of vaccines.
Background Contamination
Background contamination is extraneous particles introduced accidentally during sample analysis or production.
Antibiotics Crisis
Drug-resistant diseases are increasing worldwide and the pharmaceutical industry and policy-makers must find new workable solutions for preventing the flood of superbugs.
Peer Review
Definition of peer review in medical publishing
Medical Student Ties
Most medical school students and residents have some interaction with pharmaceutical industry representatives or receive industry gifts while in training. Attitudes are divided over whether this interaction negatively affects future career decision-making.
Rating Clinical Trials
The Society for Clinical Trials awards outstanding trials each year.

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